Streamlined Operations with Labthink’s Patented Touch System

At Labthink, we believe that simplicity drives efficiency. That’s why our Leak Tester and Leak Burst Tester feature an innovative intelligent touch operating system. This industrial-grade touchscreen system makes leak testing easier than ever with one-touch operation and a bilingual interface (Chinese and English). The Labthink Leak Tester simplifies complex testing processes, reducing the need for specialized training. Operators can quickly adapt to the system, making it easy to perform various tests with precision and confidence. With Labthink’s intuitive touch technology, your team can focus on results, not on complicated setups.

Reliable Data Storage and Security for Smooth Testing

Reliability is at the core of the Labthink Leak Tester and Leak Burst Tester. Our testers come equipped with automatic data storage and power failure memory, ensuring no test data is lost during unexpected power interruptions. The Labthink Leak Burst Tester has a storage capacity for up to 1200 test records, allowing your business to securely store a large volume of valuable data. To further enhance security, the Labthink Leak Tester features multi-level user management with password protection, ensuring that only authorized personnel can access and modify test results. This combination of data reliability and security ensures smooth, uninterrupted testing every time.

Seamless Data Transfer and Integration with Optional Features

In today’s digital world, seamless data transfer is essential. The Labthink Leak Tester is designed to facilitate smooth communication with other systems, thanks to advanced connectivity features like USB ports and an optional micro-printer for easy data printing. Additionally, businesses can take advantage of our DataShield™ System, which offers advanced data management capabilities and integration with your existing information systems. This feature supports compliance with industry regulations, such as GMP, while also improving operational efficiency. With these optional features, the Labthink Leak Tester enables businesses to optimize their workflow while ensuring data integrity.

Conclusion

With the Labthink Leak Tester and Leak Burst Tester, companies can enjoy cutting-edge technology, simplified operations, and advanced data management, all in one package. From the patented intelligent touch operating system to seamless data transfer and secure data storage, Labthink is setting the standard for leak testing technology. Choose Labthink today for a future-proof solution that enhances both efficiency and accuracy in your leak testing processes.

Basic Applications: Comprehensive Testing for Flexible Packaging

At Labthink, we understand that flexible packaging is critical to many industries. That’s why our Seal Tester and Seal Strength Test Machine are engineered to provide precise, reliable testing for plastic composite bags, flexible tubes, and more. Whether you’re testing plastic films, aluminum films, or composite films, Labthink’s equipment is designed to measure compression resistance and seal integrity with unparalleled accuracy. These machines are essential in industries ranging from food packaging to pharmaceuticals, where seal reliability is crucial for ensuring product protection and shelf-life.

Extended Applications: High-Pressure and Burst Testing for Specialized Products

In addition to basic testing, Labthink’s Seal Strength Test Machine is equipped with advanced capabilities to handle more specialized applications. One of the standout features is the ability to conduct burst tests of blister packs, ensuring that your packaging can withstand extreme internal pressures. Labthink also offers robust solutions for testing the seal performance of aerosol valves, widely used in products like medical sprays, hair care products, and food packaging. Furthermore, our machines can test tamper-evident closures, which are critical in products such as bottled beverages, edible oils, and even pharmaceutical packaging, providing businesses with an extra layer of protection for their products.

High-Performance Features: Ensuring Accurate, Reliable Results for Every Test

At Labthink, we don’t just stop at basic functionality. Our Seal Tester and Seal Strength Test Machine are built to deliver high-pressure tests up to 1.6MPa, ensuring your packaging can endure extreme conditions. These machines also come equipped with advanced features like the creep test and creep to failure test, which simulate real-world stress and assess the durability of seals over time. These tests are invaluable for businesses aiming to produce packaging that maintains its integrity under various pressures, from handling and transportation to varying environmental conditions.

Conclusion

The Labthink Seal Tester and Seal Strength Test Machine offer comprehensive testing solutions for businesses in industries such as food, pharmaceuticals, cosmetics, and more. Whether you’re testing plastic composite bags, blister packs, or aerosol valves, Labthink provides high-quality, reliable machines designed to enhance product safety and packaging performance. With high-pressure testing, advanced features, and precise measurements, Labthink ensures your packaging stands up to the highest standards of quality and durability.

Understanding Seal Strength and Its Importance

Seal strength testing is crucial for determining whether a package can withstand the stresses it encounters during transportation, storage, and handling. Packaging materials like flexible pouches, aseptic containers, and plastic caps all need a secure seal to ensure the contents remain intact and uncontaminated. Leak testers measure the ability of these materials to maintain a seal under different conditions.

At Labthink, we recognize the need for accurate, consistent results. Our Leak and Seal Strength Tester provides a reliable method for assessing these critical factors. The tester’s multiple modes, including burst tests and pressure-retaining tests, offer comprehensive insights into the packaging’s performance. By conducting these tests, manufacturers can be sure their packaging meets the required safety and quality standards.

Key Features of the Leak and Seal Strength Tester

One of the standout features of Labthink’s Leak and Seal Strength Tester is its ability to offer multiple testing modes. These include burst tests, creep tests, and even the ability to perform non-standard tests. This flexibility ensures that you can test various aspects of packaging strength under a wide range of conditions.

Another valuable feature is the real-time monitoring of gas inlet flow during testing. This ensures that the conditions remain uniform and controlled throughout the process, leading to highly repeatable test results. The tester’s interface is intuitive, with an industrial-grade touch screen that simplifies operation, while the automatic data storage ensures no test information is lost, even in the event of a power failure.

Why Choose Labthink’s Leak and Seal Strength Tester?

What sets the Labthink Leak and Seal Strength Tester apart is not only its accurate performance but also its ease of use. The tester is equipped with a patented intelligent touch operating system that allows for one-click operations and easy access to important data. With options for real-time monitoring and automatic statistics of test results, it makes testing more efficient and less prone to human error.

Additionally, the instrument is designed for both routine and specialized tests, making it suitable for a wide variety of applications. Whether you’re dealing with flexible packaging or tamper-evident closures, the Leak and Seal Strength Tester offers precise and consistent testing.

Conclusion

In the world of packaging, ensuring that your seals hold up to stress and external pressures is non-negotiable. The Leak and Seal Strength Tester by Labthink provides a reliable, automated method to test and guarantee the integrity of your packaging materials. With multiple testing modes, advanced monitoring features, and intuitive operation, this tool is an essential part of any packaging quality assurance program. Whether you’re testing burst pressure or seal integrity, you can trust Labthink to deliver consistent and accurate results every time.

Extended Applications: Advanced Testing for Specialized Packaging Solutions

Labthink’s dedication to quality extends beyond basic testing to encompass specialized packaging solutions. Our seal tester for bottles and other advanced testing machines come equipped with features tailored to meet specific industry requirements. The Seal Strength Test Machine excels in conducting burst tests for blister packs, aerosol valves, and pilfer-proof closures. Whether you are verifying the seals of aerosol valve sprays used in medical applications or ensuring the integrity of tamper-evident closures for food products, Labthink delivers the most reliable and accurate results. This capability is particularly beneficial for industries that require stringent compliance with safety regulations, as it helps you maintain consumer trust and brand reputation.

High-Pressure Testing: Ensuring Seal Integrity Under Extreme Conditions

In a market where packaging must withstand diverse conditions, Labthink’s seal tester and seal strength test machine are designed to perform high-pressure tests up to 1.6MPa. These tests are crucial for confirming that your packaging can endure extreme pressure scenarios without compromising seal integrity. Our machines offer comprehensive testing capabilities, including creep tests and creep-to-failure tests, making them indispensable for industries that demand high-performance packaging solutions. The ability to simulate extreme conditions allows you to proactively identify weaknesses in your packaging, ensuring that your products are sealed to perfection and ready for market challenges.

Customized Solutions and Expert Support

At Labthink, we understand that every business has unique testing requirements. That’s why we offer customized solutions tailored to your specific needs. Our team of experts is always available to provide support, ensuring you get the most out of our seal tester for bottles and other testing equipment. We believe that effective collaboration leads to better outcomes, and we are committed to helping you achieve your packaging quality goals.

Conclusion: Trust Labthink for Your Seal Testing Needs

When it comes to ensuring the quality and reliability of your packaging, Labthink is your trusted partner. Our seal tester and seal strength test machine provide accurate, reliable, and efficient testing solutions to help you maintain product integrity. By choosing Labthink, you are investing in the performance of your products, ensuring they meet the highest standards in the market. Trust Labthink to deliver the precision testing you need to maintain your competitive edge in the packaging industry. Let us help you seal the deal with quality you can depend on.

• Package leak testing verifies the sterile barrier integrity of medical and pharmaceutical containers to prevent atmospheric ingress and contamination.
• Deterministic testing, such as a vacuum decay leak test, quantifies pressure changes to provide objective, repeatable data.
• Regulatory compliance (e.g., USP <1207> and ISO 11607) requires deterministic, high-precision instrumentation rather than probabilistic, subjective testing methods.

Container Closure Integrity Test (CCIT) is a standardized quality assurance protocol designed to detect structural breaches in sealed containers. In the medical and pharmaceutical sectors, maintaining sterile barrier integrity is critical for shelf-life preservation.

Atmospheric ingress (the entry of outside air or moisture) into a sealed package is associated with an increased risk of instability, leading to rapid oxidation, accelerated spoilage, or the total loss of sterility. Testing these barriers aims to manage these risks. Identifying defects relies heavily on advanced vacuum decay analysis to ensure compliance with strict clinical safety standards.

How Does Pressure Change Reveal Package Leaks?

When a package is placed in a vacuum environment, the external pressure drops significantly compared to the internal pressure. This physical stress forces any trapped air inside the package to push outward. In defective packaging, this gas escapes through “tortuous paths” (complex, winding microscopic channels within the sealing material).

The United States Pharmacopeia (USP <1207>) provides strict guidelines on how to classify the detection of these paths. The standard categorizes testing methodologies into two distinct clinical frameworks:

l  Probabilistic Methods: Tests like Visual bubble emission rely on human observation and statistical probability. They are effective for identifying severe structural failures but leave room for subjective interpretation.

l  Deterministic Methods: Tests like quantitative vacuum decay, utilize calibrated sensors to measure exact pressure changes. They provide objective, numerical data that removes human error, aligning with strict pharmaceutical auditing requirements.

How to Do ASTM Conforming Leak Test?

Labthink C690 series leak detection systems adopt objective / deterministic, quantitative inspection technology that is non-destructive and non-invasive to the package being tested. This technology requires no sample preparation and performs leak detection based on the basic principles of physics. It is suitable for laboratory offline testing and QA/QC statistical process control. The test cycle takes only a few seconds, non-destructive to both product and package.

According to the methodology described in ASTM F2338, FDA package integrity testing method basing on vacuum decay principle, the standard procedure for conducting this test includes the following steps:

1. Place the package sample in test chamber
2. The test chamber is pressurized to a preset pressure level then isolated from the pressure source.
3. The decrease of chamber pressure (pressure decay) is monitored over a specified time period.
4. Detected pressure drop suggests that air is leaking into the tested package sample. A gross, medium or micron leak of the package can be identified based on predetermined pressure decay limits.

What Are the Advantages of a Non-Destructive Leak Test?

A non-destructive leak test, such as vacuum decay, protects high-value pharmaceutical samples from water contamination, allowing intact products to return safely to the production line. By eliminating the “human eye” factor, these systems utilize precise transducers to quantify microscopic pressure drops in a completely dry testing environment.

When testing high-value parenteral packaging (such as specialized glass vials or prefilled syringes), destructive water immersion is highly inefficient and creates significant material waste. The vacuum decay leak test addresses this by isolating the sample in a tightly conforming, dry testing cell.

This deterministic method offers exceptional sensitivity and objectivity. Advanced instruments, such as the Labthink C690 series, utilize microflow detection technology capable of identifying leak apertures as small as 1 µm. Because the system relies entirely on pressure transducers rather than visual observation, the data is entirely objective and repeatable.

Furthermore, the dry testing environment eliminates the risk of “boiling water” false positives. In high-vacuum bubble tests, dissolved gases in the testing water can occasionally expand and mimic a package leak, confusing human operators. Vacuum decay bypasses this physical phenomenon entirely, providing a clinically sound and mathematically precise leak rate.

Why Are High-Precision Leak Detection Instruments Important?

Regulatory bodies require quantitative, traceable data that uncalibrated manual methods cannot provide. High-precision instruments ensure exact pressure control and automated data integrity to meet strict Good Manufacturing Practice (GMP) and FDA compliance standards.

In clinical packaging, informal quality checks like manual “squeeze tests” or DIY acrylic vacuum chambers routinely fail regulatory audits. These methods lack precise calibration and cannot produce the repeatable data required by ISO 11607 (Packaging for terminally sterilized medical devices).

To meet these standards, facilities rely on advanced solutions:

l  The C690H Nondestructive Package Leak Detector: This system ensures accuracy by utilizing dual-sensor architectures and NIST-traceable calibration. It provides microflow data without altering the sample.

l  The C660B Leak and Seal Strength Tester: It functions as a highly controlled gross leak bubble tester while also providing quantitative seal strength data.

l  Automated Data Integrity: To comply with FDA 21 CFR Part 11 and GMP, these modern systems feature digital record-keeping. They automatically log audit trails, require multi-level electronic signatures, and prevent raw data manipulation, ensuring that all clinical reporting is secure and verifiable.

How Does Vacuum Leak Testing Apply Across Different Manufacturing Industries?

Industries utilize package leak testing to manage specific environmental risks, from maintaining sterility in medical vials to preserving gas mixtures in food packaging. The chosen method depends on the product’s sensitivity to moisture, oxygen, and atmospheric pressure changes.

While the fundamental physics of differential pressure remain the same, the application varies significantly by sector:

l  Pharmaceuticals: The industry relies heavily on non-destructive options. High-value biological drugs and lyophilized (freeze-dried) powders are highly sensitive to moisture; even a microscopic breach can ruin a batch.

l  Food Packaging: Manufacturers use leak testing to ensure that MAP (Modified Atmosphere Packaging) remains stable. MAP involves replacing oxygen with nitrogen or carbon dioxide to slow decay. A leak allows ambient oxygen to return, accelerating spoilage.

l  Electronics and Industrial: Sensitive semiconductors and microchips require protection from moisture ingress. Vacuum leak testing ensures that protective foil pouches remain hermetically sealed, protecting the components from condensation during high-altitude air transit.

Conclusion

Establishing a compliant quality control protocol aims to manage the severe risks associated with compromised sterile barriers. For technical consultations on integrating the high-end package testing instruments into your GMP-compliant workflow, contact the packaging engineering experts at Labthink.

Revolutionizing Leak and Seal Integrity Testing with Multiple Test Modes

The C660M Leak Tester stands out by offering a variety of test modes that ensure a comprehensive evaluation of seal integrity. These modes include burst testing, creep testing, creep-to-failure testing, and pressure retaining tests, enabling businesses to tailor their tests to suit the specific characteristics of their products. With these versatile testing options, manufacturers can assess the strength and durability of seals under different conditions. Additionally, the C660M provides flexibility by supporting both restraint and unrestrained distension testing methods, giving customers the ability to choose the most suitable approach for their testing needs. Whether you’re dealing with thin films, rigid containers, or complex products, the C660M Leak Tester offers a comprehensive suite of tests to ensure seal integrity across various applications.

Automated Testing for Effortless and Accurate Results

The C660M Leak Tester incorporates an automated testing process that significantly reduces manual intervention, increasing both efficiency and accuracy. With real-time display of test curves, operators can monitor the test in progress and make adjustments if necessary. The C660M also features automatic data statistics, which provide immediate insights into test results, enabling businesses to quickly identify any issues. This automation streamlines testing workflows, allowing companies to reduce testing time and improve productivity while ensuring consistent and reliable results every time.

Guaranteed Performance with High-Quality Components and Real-Time Gas Flow Monitoring

At Labthink, we are committed to providing top-tier performance and reliability in every product we offer. The C660M Leak and Seal Integrity Tester is equipped with high-quality components sourced from trusted global manufacturers, ensuring durability and long-lasting performance. Additionally, the C660M features innovative real-time gas inlet flow monitoring, which ensures uniform testing conditions during the test process. This technology enhances the repeatability and accuracy of test results, offering businesses a high level of confidence in the integrity of their products. With guaranteed performance and advanced monitoring, the C660M Leak Tester delivers consistent and dependable results for a variety of testing applications.

Precision and Flexibility for Diverse Testing Needs

The C660M Leak Tester provides unmatched flexibility, allowing businesses to select non-standard test ranges for specialized applications. Whether you’re conducting routine testing or specialized research, the C660M offers the versatility needed to handle a wide range of testing requirements. The C660M’s comprehensive capabilities and user-friendly interface make it an ideal solution for companies looking for precision and reliability in leak and seal integrity testing. With Labthink, you can trust that your products undergo thorough and accurate assessments to meet the highest quality standards.

Conclusion

The Labthink C660M Leak Tester and Seal Integrity Tester is the perfect solution for businesses looking to ensure the reliability and performance of their products. With advanced test modes, an automated testing process, and high-quality construction, the C660M delivers the precision and consistency needed for effective leak and seal integrity testing. Trust Labthink to provide the tools that help your business maintain the highest standards of quality and safety.

Comprehensive Testing Solutions Offered by Labthink

As a leading name in the field of packaging material testing, Labthink provides a wide array of tests designed to assess every aspect of packaging performance. Our Packaging Safety Testing Center offers specialized testing services that cover tensile strength, barrier properties, burst resistance, and more. Each of these tests plays a critical role in verifying the quality and safety of packaging materials.

For the pharmaceutical industry, where product safety is even more critical, packaging material testing in pharmaceutical industry requires strict adherence to regulatory standards. At Labthink, we ensure that your packaging materials undergo rigorous tests to meet these requirements, giving you the peace of mind that your products are safely protected throughout their lifecycle.

The Importance of Skilled Lab Technicians

At Labthink, the success of packaging material testing is driven not only by advanced equipment but also by the expertise of our lab technicians. Our technicians are highly skilled in executing a wide range of tests, tailoring protocols to the unique needs of each client. Their deep knowledge of packaging materials allows them to identify potential weaknesses and suggest improvements for enhanced performance.

This expertise is especially important when conducting packaging material testing in pharmaceutical industry—where precision and compliance with regulatory requirements are non-negotiable. Our team ensures that every test is carried out meticulously, providing accurate and reliable results that help our clients make informed decisions.

Advancing Industry Standards and Research Initiatives

Labthink is committed to pushing the boundaries of packaging material testing. We actively participate in global research initiatives and collaborate with leading research institutions to develop and revise industry standards. By staying involved in the creation of new testing protocols, Labthink ensures that our clients always have access to the latest methodologies and technologies.

In the packaging material testing in pharmaceutical industry, where compliance with stringent regulations is crucial, this commitment to advancing industry standards is invaluable. Our ongoing involvement in shaping the future of packaging testing ensures that our clients can stay ahead of regulatory changes and market demands.

Conclusion: Choose Labthink for Reliable Packaging Material Testing

For businesses in need of reliable packaging material testing, Labthink is the trusted partner. Our comprehensive testing solutions, expert technicians, and dedication to advancing industry standards make us the ideal choice, particularly for the pharmaceutical sector. Let Labthink help you ensure the integrity of your packaging materials, so you can deliver safe, high-quality products to your customers.

Understanding the Importance of Leak Rate Testing

Leak rate testing involves determining the amount of gas or liquid that escapes through a sealed area over a set period of time. It’s particularly important for products that require airtight packaging, such as food, pharmaceuticals, and medical devices. With a Labthink leak tester, you can monitor the integrity of seals in real-time, ensuring that every product meets safety standards. The leak and seal strength tester helps you quantify the seal strength, burst pressure, and overall seal integrity, which are crucial for understanding how well a product performs under stress.

Different Methods for Leak Rate Testing

There are several methods for leak testing, and the choice of method depends on the specific product and its requirements. At Labthink, we offer multiple testing modes, such as burst tests, creep tests, and pressure-retaining tests. These modes give you flexibility when determining how a product behaves under various pressure conditions. With the leak and seal strength tester, you can choose between restrained and unrestrained distension, providing a comprehensive analysis of the seal’s performance.

The leak tester at Labthink also features real-time monitoring of gas inlet flow, ensuring that testing conditions remain consistent throughout the process. This innovative feature contributes to the high repeatability and reliability of test data, helping you maintain a high standard for leak rate testing.

Real-Time Monitoring and Data Management

One of the standout features of Labthink’s leak and seal strength tester is its patented intelligent touch operating system. The system allows for simplified operation with a user-friendly interface, and the ability to store up to 1,200 test records. This data can be easily exported via USB ports or a micro-printer. Additionally, Labthink’s leak tester provides power failure memory, preventing data loss during an unexpected shutdown.

For added convenience, the instrument also supports both Chinese and English language interfaces, making it easier for teams across the globe to use. The leak and seal strength tester conforms to GMP (Good Manufacturing Practice) standards, ensuring that your leak rate tests meet regulatory requirements.

Ensuring Consistency and Accuracy in Leak Rate Testing

In any manufacturing environment, consistency and accuracy are key to ensuring the quality and safety of the final product. At Labthink, we understand the importance of reliable testing equipment. Our leak tester is designed to provide high-accuracy results with minimal variation, thanks to its precision engineering and real-time data monitoring.

The choice of materials used in manufacturing the instrument plays a significant role in the leak and seal strength tester’s performance. Labthink only sources its main components from well-known global manufacturers, ensuring that each unit delivers consistent and reliable results.

Conclusion

In conclusion, a robust leak rate testing process is vital for guaranteeing product safety and integrity. With the help of Labthink’s advanced leak tester, manufacturers can confidently assess the strength and quality of seals, ensuring that each product adheres to the highest standards. By using our leak and seal strength tester, you can simplify your testing process, improve efficiency, and maintain consistency in your production line. At Labthink, we are committed to helping you achieve the highest level of quality assurance through accurate and reliable testing solutions.

Seal Strength

Seal strength, often measured as seal peel strength, is a quantitative measure of the force required to separate the sealed layers of a package. It evaluates the material resistance of the seal itself, indicating how well the fused materials hold together under stress. This property is crucial for ensuring packages can withstand handling, transportation, and stacking forces without the seal peeling open. A package with high seal strength may still have microscopic channels that allow the passage of gases or contaminants, which is a separate concern. Testing for this typically involves using a tensile tester or a specialized leak tester that applies a controlled, peeling force to the seal area. The results are usually expressed in units of force per unit width, such as Newtons per 15mm, providing a clear, numerical value for quality control and comparison against specifications.

Seal Integrity

Seal integrity refers to the continuity and wholeness of a seal, acting as a barrier against the passage of gases, microbes, or other contaminants. It is an assessment of whether the seal is physically complete and free from leaks, channels, or weak spots. A package can possess high seal strength but poor integrity if there are pinholes or inconsistent fusion along the seal’s length. This characteristic is vital for products requiring sterility, modified atmospheres, or protection from moisture and oxygen. Methods to test integrity include bubble emission, dye penetration, and vacuum decay tests. We at Labthink provide instruments designed to detect these minute breaches that strength tests might miss. Maintaining seal integrity is essential for product shelf life, safety, and compliance with industry regulations, ensuring the package performs its primary protective function effectively.

Strength Versus

The core difference lies in what each property assesses: strength measures mechanical resistance to separation, while integrity test ensures there are no micro-leaks, pinholes, or gaps that would allow bacteria or air to compromise the sterile environment. Think of seal strength as the “brawn” of the seal—its ability to resist being pulled apart. In contrast, seal integrity is its “health”—an indication of being fully intact and continuous without any breaches. A robust, strong seal might still fail to protect its contents if integrity is compromised by an invisible micro-leak. Conversely, a seal with perfect integrity might be too weak to survive distribution. Therefore, both parameters are critical and often require separate, dedicated testing protocols for a comprehensive package evaluation. A complete quality control strategy must include assessments for both to guarantee that the package is both durable and hermetically secure throughout its lifecycle.

Conclusion

Seal strength is usually determined via a Peel Test (ASTM F88). A strip of the seal is pulled apart by a (tensile tester. Labthink C610H Auto Tensile Tester is professionally applicable to measurement of tensile, peeling, tearing, heat sealing, adhesive, puncture force, opening force, pulling force of various soft package materials. It conforms to international standards including ISO 37, ASTM F88, ASTM E4, ASTM D882, ASTM D1938, ASTM D3330, etc.

Seal Integrity is tested by specially designed leak testers. Labthink C660M Leak and Seal Strength Tester, a piece of seal testing equipment that functions as a leak tester and seal integrity tester. It performs evaluations including seal strength testing, burst-pressure leak testing, and compression resistance testing. The tester is applicable to the quantitative determination of seal strength and burst pressure for various flexible packages, aseptic packages, and plastic tamper-evident closures. It is designed to comply with test standards such as ISO 11607-1, ISO 11607-2, ASTM F1140, and ASTM F2054.

Labthink C690M Nondestructive Package Leakage Detector is based on the vacuum decay method and pressure decay method, and is designed and manufactured according to ASTM F2338 and other standards. It is professionally suitable for the trace leakage detection of various drug packaging such as vials, ampoule bottles, cartridge bottles, infusion bottle, and prefilled syringes and so on.

Bubble Emission Leak Tests

Bubble emission leak testing is a straightforward, qualitative method used to identify the location of a leak. The package is submerged in a water tank and internally pressurized with air. An inspector then visually observes the package for a steady stream of rising bubbles, which indicates a leak path. This method is effective for detecting larger leaks and is relatively low-cost, but it is operator-dependent and may not be sensitive enough for very small, micron-sized leaks. It is a common manual procedure for finished goods and is often used as a go/no-go test. For more precise and automated quantitative measurements, a dedicated seal tester is typically employed in a laboratory or production environment to provide more reliable and repeatable data.

Vacuum Decay Leak Detection

Vacuum decay leak detection is a non-destructive, quantitative test method ideal for rigid and semi-rigid packages. The package is placed in a sealed test chamber, which is then evacuated to a predetermined vacuum level. The system monitors the vacuum level for a specific duration; a rise in pressure inside the chamber indicates that air has leaked out of the package. This method is highly sensitive and can detect very small leaks. It provides objective pass/fail results and is well-suited for automated production line integration. We at Labthink develop instruments based on this principle, which is widely used for testing vials, ampoules and other sealed containers in the pharmaceutical and food industries to ensure product integrity and compliance with regulatory standards.

Dye Penetration Leak Test

Dye penetration testing is a destructive method used specifically to locate leaks in the seal area of porous and non-porous medical packaging, such as Tyvek pouches. A liquid dye is introduced to the seal area, the leak can be observed by the operator. While highly effective for pinpointing seal defects, this method destroys the test sample and requires manual inspection. It is a recognized standard for validating the sterility barrier of medical device packaging, ensuring that no contaminants can enter through faulty seals during storage and handling.

Conclusion

Labthink C660M Leak and Seal Strength Tester, a piece of seal testing equipment that functions as a leak tester and seal integrity tester. It performs evaluations including seal strength testing, burst-pressure leak testing, and compression resistance testing. The tester is applicable to flexible packages, aseptic packages, plastic tamper-evident closures, and flexible tubes. It is designed to comply with test standards such as ISO 11607-1, ISO 11607-2, ASTM F1140, and ASTM F2054.

Labthink C690M Nondestructive Package Leakage Detector is based on the vacuum decay method and pressure decay method, and is designed and manufactured according to ASTM F2338 and other standards. It is professionally suitable for the trace leakage detection of various drug packaging such as vials, ampoule bottles, cartridge bottles, infusion bottle, and prefilled syringes and so on.